Neurology | Beckman Coulter

 

Rising to a Global Challenge

As a growing cause of death and morbidity among older adults worldwide, neurology diseases such as Alzheimer’s and dementia are creating unprecedented challenges across health care. Heterogeneous in nature, presenting with a wide variety of symptoms, these highly complex diseases carry unique diagnostic challenges and limitations.1


At Beckman Coulter we believe blood-based neurology biomarkers will forever change how diseases are investigated, diagnosed, and monitored. From disease diagnosis and prognosis to drug discovery and development, the opportunities for accessible and scalable diagnostic neurodegenerative testing will reimagine the standard of patient care.

Neurology prevalence by the numbers

Parkinson's Disease, Traumatic Brain Injury, Multiple Sclerosis and Dementia neurology diseases

Fueled by epidemiological factors such as population growth, longer life expectancies, and the availability of novel therapeutics, we are facing a population that requires scalable, affordable, and easy-to-use testing in the core laboratory. We anticipate an unprecedented demand for reliable, highly sensitive blood-based testing.



 

 

“We are investing in our immunoassay technology to develop new, blood-based, high throughput, high sensitivity assays to detect and measure neurological biomarkers at a scale to address the global challenge."
Kevin O'Reilly
President, Beckman Coulter Diagnostics


 

Improving Access through Scalability

At Beckman Coulter we are committing to advancing neurological patient care to make it more accessible to people around the world. 
With 90 years of diagnostic innovation and our legacy in workflow efficiency, reliability, and scalability, we are advancing the future of neurodegenerative diagnostics. Today, our solutions run over 1 million tests per hour, impacting over 1.2 billion patients per year around the world, and our biomarkers are unlocking more clinical insights than ever before, providing meaningful, actionable data.

Neurological Biomarkers

Neurological biomarker assays for Research Use Only (RUO)
• p-Tau217
• β-Amyloid 1-42
• GFAP
• NfL
• APOE e4

 

Reliable and highly sensitivity assay detection for your most sensitive biomarkers. Experience high-throughput, fully automated immunoassay testing with reliable and highly sensitive assay detection for your most critical biomarkers.

GFAP

P-Tau217

Learn More


References:

1. Erkkinen MG, Kim MO, Geschwind MD. Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. Cold Spring Harb Perspect Biol. 2078;70(4):a033778. Published 2018 Apr 2. doi:70.1101/cshperspect.a033118

2. New study predicts the number of people living with Alzheimer’s disease to triple by 2050. Alzheimer’s Disease International. 2022. Accessed April 30, 2024. https://www.alzint.org/news-events/news/new-data-predicts-the-number-of-people-living-with-alzheimers-disease-to-triple-by-2050/

3. Parkinson disease. World Health Organization. 2023. Accessed April 30, 2024.
https://www.who.int/news-room/fact-sheets/detail/parkinson-disease#:~:text=The%20prevalence%20of%20PD%20has%20doubled%20in,5.8%20million%20disability%20adjusted%20life%20years%20

4. GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators. (2019). Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology, 18(1), 56–87. doi: 10.1016/S1474-4422(18)30415-0

5. Dewan, M. C., Rattani, A., Gupta, S., Baticulon, R. E., Hung, Y.-C., Punchak, M., … Park, K. B. (2018). Estimating the global incidence of traumatic brain injury. Journal of Neurosurgery, 130(4), 1080–1097. doi: 10.3171/2017.10.JNS17352

6. Multiple sclerosis. World Health Organization. 2023. Accessed April 30, 2024.
https://www.who.int/news-room/fact-sheets/detail/multiple-sclerosis#:~:text=It%20is%20estimated%20that%20over,young%20adults%20and%20in%20females