Sepsis Diagnosis

Sepsis is a worldwide problem that can cause devastating patient consequences and incur significant healthcare costs. But diagnosing sepsis is challenging. Delays in diagnosing sepsis and initiating treatment result in increased symptom severity and patient risk, higher rates of long-term complications and mortality, and greater costs to healthcare systems.

Early sepsis detection improves patient prognosis and reduces the cost of sepsis-related care. Beckman Coulter is currently the only company providing all IVD testing modalities for sepsis diagnosis and management.¹

White Paper Early Sepsis Detection: Reducing Mortality Rates and Hospital Costs²

Sepsis is a global problem in developed and resource-poor countries alike, and it is increasing at an annual rate of 1.5%, meaning that it is now killing more individuals than prostate cancer, breast cancer and HIV/AIDS combined³. Read more about how together, we can detect sepsis earlier; resulting in better patient prognosis and reduced cost.⁴

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The Early Sepsis Indicator uses the DxH series hematology analyzer's enhanced Coulter technology, which offers near native-state cellular characterization. The analyzer's powerful VCS 360 technology can uniquely detect morphological changes in monocytes, cells that play a role in the dysregulated immune response to sepsis. Identifying these monocyte morphological changes provides insight into possible sepsis earlier than other indicators.

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References:

¹Sepsis related portfolio is comparison for major IVD companies January 2019

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²For more information, download the Instructions for Use for the product

Vidant Beaufort Hospital "The Third-leading Cause of Death: Sepsis" www.thewashingtondailynews.com/2017/07/08/the-third-leading-cause-of-death-sepsis/, 8 Jul 2017. Accessed 19 Mar. 2018.
Kumar G, Kumar N, Taneja A et al. "Nationwide Trends of Severe Sepsis in the Twenty First Century (2000–2007)." Chest, vol. 16. 2011, pp. 1223–31. doi: 10.1378/chest.11-0352.
Hall MJ, Williams SJ, DeFrances CJ, Golosinsky A. "Inpatient Care for Septicemia or Sepsis: A Challenge for Patients and Hospitals." www.cdc.gov/nchs/data/databriefs/db62.pdf, June 2011. Accessed 2 May 2018.

⁴

Rhodes A, Evans LE, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive care medicine 2017;43:304-77
Jones SL et al. "Reductions in Sepsis Mortality and Costs After Design and Implementation of a Nurse-based Early Recognition and Response Program." Jt Comm J Qual Patient Saf, vol. 41, no. 11. 2015, pp. 483–91.
Judd WR, Stephens DM, Kennedy DA. "Clinical and Economic Impact of a Quality Improvement Initiative to Enhance Early Recognition and Treatment of Sepsis." Ann Pharmacol, vol. 48, no. 10. 2014, pp. 1269–75.

Information addressed to health professionals. The products presented on this site are for professional use only, and, where applicable, comply with the requirements of the IVD Directive 98/79 / EC. Instructions for use must be consulted before using these products.

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U.S. Government Users Restricted Rights - As per GSA ADP Schedule Contract with Beckman Coulter, Inc., the use, duplication or disclosure is restricted as follows: Beckman Coulter hereby authorizes user to copy those documents published on the World Wide Web by Beckman Coulter, for noncommercial use, and only within the user's organization. Except as expressly provided above, nothing contained herein shall be construed as granting any license or right under any Beckman Coulter copyright. Nothing contained herein shall be construed as granting by implication, estoppel or otherwise any license or right under any patent or trademark of Beckman Coulter or any third party.

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Sepsis Diagnosis

White Paper Early Sepsis Detection: Reducing Mortality Rates and Hospital Costs2

Video Strengthen Clinical Decision-Making

White Paper Early Sepsis Detection: Reducing Mortality Rates and Hospital Costs²